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涎腺导管癌(SBC)是涎腺的一种不常见肿瘤,因其组织学与乳腺导管癌极为相似而得名。文献中已有15例报告,均累及腮腺。在组织学上,表现为筛状、乳头状排列及粉刺样坏死,分别或同时存在于同一病损中。本文报告两例腮腺区涎腺导管癌,重点描述其组织学和超微结构特点。因该肿瘤预后较差,因此作者认为在形态学和临床特点的基础上与其他肿瘤鉴别,具有重要意义。例一:59岁白人,男性,因腮腺区肿胀而入院。冰冻切片检查后,行右腮腺切除及颈部解剖。术后组织10％甲醛固定、石蜡包埋制片,HE染色备光镜观察。标本用2％戊二醛磷酸缓冲液固定,1％四氯化锇再固定,蔗糖磷酸缓冲液冲洗后,浸于0.5％水性双氧铀醋酸盐中过夜。标本用乙醇脱水包埋于环氧类树脂中。超薄切片用枸橼酸铅染色作电镜观察。例二:63岁女性,白人,左腮腺发现无痛性结节两
Sacral ductal carcinoma (SBC) is an uncommon tumor of the parotid gland. It is named because its histology is very similar to breast ductal carcinoma. There are 15 reports in the literature, all involving the parotid gland. Histologically, the appearance of the squamous cell, papillary arrangement, and necrosis of acne occurred separately or simultaneously in the same lesion. This paper reports two cases of parotid ductal carcinoma in the parotid gland, focusing on histological and ultrastructural features. Because of the poor prognosis of the tumor, the author believes that it is of great significance to distinguish it from other tumors on the basis of morphological and clinical characteristics. Example: A 59-year-old Caucasian, male, admitted to hospital because of swelling of the parotid gland. After the frozen section examination, right parotidectomy and neck dissection were performed. Postoperative tissues were fixed with 10% formaldehyde, embedded in paraffin, and visualized by HE staining. Specimens were fixed with 2% glutaraldehyde phosphate buffer, 1% ruthenium tetrachloride was fixed, washed with sucrose phosphate buffer, and immersed in 0.5% aqueous uranyl acetate overnight. The specimen was dehydrated with ethanol and embedded in an epoxy resin. Ultrathin sections were stained with lead citrate for electron microscopy. Example 2: 63-year-old female, Caucasian, left painful nodules found in the left parotid gland