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目的了解乙肝疫苗接种及乙型病毒性肝炎预防控制效果。方法采用纵向流行病学研究方法,对15岁以下儿童乙肝疫苗接种率、免疫成功率、发病率等进行研究。结果 1998～2009年乙肝疫苗报告接种率为93.83%,调查接种率为93.67%,首针及时接种率为92.37%;HBsAb阳性率为86.98%,其中6岁以下为89.95%;母婴阻断保护率为98.0%;接种副反应率为3.14/10万;发病率下降98.80%;15岁以下儿童发病率与1998年乙肝疫苗接种前比较下降88.48%,2000年后10岁以下儿童乙肝发病率为0～3/10万。结论兴山县乙型病毒性肝炎预防控制已实现或基本实现《2006～2010年全国乙型病毒性肝炎防治规划》目标。
Objective To understand the effect of hepatitis B vaccination and prevention and control of hepatitis B virus. Methods A longitudinal epidemiological study was conducted to investigate the hepatitis B vaccination rate, immunization success rate and incidence rate of children under 15 years of age. Results The reported vaccination rate of hepatitis B vaccine was 93.83% from 1998 to 2009, the survey inoculation rate was 93.67%, the first inoculation rate was 92.37%, the positive rate of HBsAb was 86.98%, of which 89.95% was below 6 years old. The incidence rate was 98.80%; the incidence rate of children under 15 years old was 88.48% lower than that before the hepatitis B vaccination in 1998; the incidence of hepatitis B in children under 10 years old after 2000 was 0 ~ 3/10 million. Conclusion Prevention and control of hepatitis B in Xingshan County has achieved or basically achieved the goal of “National Plan for Prevention and Control of Hepatitis B in 2006 ~ 2010”.