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高血压是严重影响人类健康的疾病,对它的研究差不多有一个多世纪。在此之前,由于一直未能弄清血压升高对于人体的生理影响,当时的医学家推测动脉压升高是为了克服增厚动脉的阻力,是为了保护肾排泄功能所必须的代偿机制,所以降压一直被视为禁忌——他们认为降压将导致人体生命危险。 直到1927年,才有一位叫做Brown的医生提出需要对高血压病人进行降压。认为不予降压,肾功能就会衰竭。他的许多同行立即对此表示质疑。幸好与此同时,切除交感神经治疗高血压的临床研究表明降压并未造成肾功能恶化,从此“血压升高是一种有益的代偿作用”的观点才被彻
Hypertension is a disease that seriously affects human health and has been studied for almost a century. Prior to this, due to the failure to understand the physiological effects of elevated blood pressure on the human body, then the medical scientists speculated that elevated arterial pressure in order to overcome the resistance of thickened arteries, in order to protect renal excretion necessary compensatory mechanism, Therefore, antihypertensive therapy has always been considered as a taboo - they believe that antihypertensive will lead to human life. It was not until 1927 that a doctor named Brown proposed the need for blood pressure reduction in hypertensive patients. Do not think that buck, renal function will fail. Many of his colleagues questioned it immediately. Fortunately, at the same time, clinical studies of sympathectomy for hypertension have shown that hypotension does not result in worsening of renal function and that “elevated blood pressure is a beneficial compensatory effect”