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目的观察早期鼻空肠内营养管在治疗SAP中的作用。方法将86例SAP患者在知情同意的基础上随机分为对照组43例,治疗组43例;两组患者均给予综合治疗,治疗组在综合治疗的基础上,待肠麻痹解除后早期应用EN;监测两组治疗10 d血淀粉酶、血清白蛋白的变化;比较两组治愈、死亡率、继发感染、并发症的发生率、平均住院天数及费用。结果监测两组治疗后血淀粉酶均较治疗前明显下降(P<0.01);治疗组血清白蛋白数值明显高于对照组,两组比较差异有显著性(P<0.01);治疗组治愈率较对照组增加,死亡率、继发感染、并发症的发生率均降低,住院天数缩短,住院费用减少。结论早期的EN是治疗SAP的重要手段,不仅可增强机体抵抗力,减少营养物质的分解,又能提高治愈率,利于疾病康复,此方法简单、方便、安全可行。
Objective To observe the role of early nasogastrointestinal tube in the treatment of SAP. Methods Eighty-six patients with SAP were randomly divided into control group (43 cases) and treatment group (43 cases). Both groups were given comprehensive treatment. On the basis of comprehensive treatment, the patients in treatment group were treated with enteral nutrition The changes of serum amylase and serum albumin in the two groups were monitored 10 days after treatment. The cure rate, mortality rate, secondary infection, complication rate, average days of hospitalization and cost were compared between the two groups. Results The serum amylase levels of the two groups after treatment were significantly lower than those before treatment (P <0.01). The values of serum albumin in the treatment group were significantly higher than those in the control group (P <0.01). The cure rate Compared with the control group, the incidence of mortality, secondary infection and complication decreased, the days of hospitalization shortened, and the cost of hospitalization decreased. Conclusion Early EN is an important means of treating SAP. It not only can enhance the body resistance, reduce the decomposition of nutrients, but also improve the cure rate and benefit the rehabilitation of the disease. This method is simple, convenient, safe and feasible.