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该文报告1例肾胚胎细胞瘤伴严重高血压时肾素增高,经肿瘤免疫组织化学证实在血管周围有含肾素细胞。病例男,10个月,厌食及全身不适2周。查体:患儿烦燥不安,血压33.3/25.9kPa,脉搏100次/分,左腹巨大不规则包块。生化分析:Na~+ 131mmol/L,K~+ 3.7mmol/L,尿素9.5mmol/L,静脉肾盂造影和CT 证实包块来自左肾。成神经细胞瘤标志的羟甲基扁桃酸和香草扁桃酸分别为16和24μmol/L 肌酸酐(正常)。开始静脉用柳胺心定和肼苯哒嗪,但未降压,故在入院后第9日行剖腹探查术,用开普通降压效果
This paper reports a case of renal blastocytoma with severe hypertension when renin increased, confirmed by tumor immunohistochemistry in the blood vessels around the renin-containing cells. Male patient, 10 months, anorexia and general malaise for 2 weeks. Physical examination: children irritable, blood pressure 33.3 / 25.9kPa, pulse 100 beats / min, huge left unabashed mass. Biochemical analysis: Na ~ + 131mmol / L, K ~ + 3.7mmol / L, urea 9.5mmol / L, intravenous pyelography and CT confirmed mass from the left kidney. Neuroblastoma markers of methylol mandelic acid and vanillyl mandelic acid were 16 and 24 μmol / L creatinine (normal), respectively. Started intravenous dihydrochloride and hydralazine, but not antihypertensive, so on the 9th post-hospital laparotomy exploration, with an open antihypertensive effect