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目的:孕妇在妊娠期间服食美沙酮,分娩后第2天,检测新生儿脐带与血清美沙酮的浓度,进而评定美沙酮浓度在预测新生儿戒断综合征(NAS)严重程度方面的应用价值。方法:选择胎龄不小于35周的新生儿作为试验对象,征得家属同意后,将其纳入本次试验。试验所需的相关信息,由孕妇提供。分娩时采集一份脐带血样本,
OBJECTIVE: Pregnant women take methadone during pregnancy. On the second day after delivery, the umbilical cord and serum methadone concentrations were measured, and then the application value of methadone concentration in predicting the severity of neonatal withdrawal syndrome (NAS) was evaluated. Methods: Newborns with a gestational age of 35 weeks or more were selected as the test subjects. After obtaining the consent of their families, they were included in the trial. The relevant information needed for the test is provided by pregnant women. A cord blood sample is collected during childbirth,