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骨巨细胞瘤(giant cell tumor,GCT)是一种具有局部侵袭性的良性骨肿瘤,主要治疗方法是手术治疗。刮除、瘤壁灭活和自体骨、异体骨或骨水泥填充是目前GCT治疗最常用的方法 [1-6]。早期报道的单纯刮除手术术后的复发率比较高,从25%~50%不等[7-12]。瘤腔周围的微小病灶残留是肿瘤复发的主要因素,因此,为了降低GCT刮除局部复发率,各种针对瘤腔周围微小病灶的辅助措施逐渐发展起来。多数研究表明,刮除术后残腔处理可以有效降低术后复发率[6-7,13]。广泛切除可以降低肿瘤的局部复发率[14-16],但是其一方面增加了手术后的并发症[17-18],另一
Giant cell tumor (GCT) is a locally aggressive benign bone tumor, the main treatment is surgery. Scraping, tumor wall inactivation and autologous bone, allogeneic bone or bone cement filling is the most commonly used method of GCT treatment [1-6]. Earlier reports of simple curettage recurrence rate is relatively high, ranging from 25% to 50% [7-12]. Therefore, in order to reduce the local recurrence rate of GCT, various auxiliary measures targeting the tiny lesions around the tumor cavity have been gradually developed. Most studies have shown that residual curettage after curettage can effectively reduce the postoperative recurrence rate [6-7,13]. Extensive resection can reduce the local recurrence rate of tumors [14-16], but it increases the postoperative complications on the one hand [17-18] and the other