抗生素与血清蛋白结合对抗生素抗菌活性的影响是人们争论的问题。人们认为抗生素的药理作用与感染部位游离药物浓度有关,但还不清楚是否低蛋白结合率抗生素其抗菌作用优于高蛋白结合率抗生素。本文应 Antibiotics and serum protein binding antibiotics antibacterial activity is the issue of debate. It is thought that the pharmacological action of antibiotics is related to the free drug concentration at the infected site, but it is unclear whether the low protein binding rate antibiotics have better antibacterial activity than the high protein-bound antibiotics. This article should be