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目的了解近6年来就诊于我院的胃癌患者流行病学及临床病理资料的特点,为疾病的诊断与评估提供帮助。方法将2004年1月至2009年12月期间于我院进行手术治疗的958例胃癌患者作为研究对象,对其一般资料、肿瘤病理类型、发生部位、临床分期等进行回顾性分析。结果 958例胃癌患者中,男697例(72.8%),女261例(27.2%)。年龄26~91岁,平均62.6岁;高发年龄为46~65岁组,占49.4%(473/958),其后依次为≥66岁组及≤45岁组,分别为42.3%(405/958)和8.3%(80/958)。病理的大体分型上,BorrmannⅡ型占大多数(70.1%);病理类型以腺癌居多,占82.3%,印戒细胞癌占7.8%;分化程度以低分化为主,占46.9%。发生部位以贲门居多,占53.0%。TNM临床分期中以Ⅲ期为主,占47.4%。结论①胃癌多见于中老年男性患者,以贲门部低分化腺癌多见,贲门癌发病率明显高于胃窦癌;②在胃癌患者中,恶性程度较高的低分化、印戒细胞癌中所占比例最高者为相对较年轻的患者(≤45岁组);③行手术治疗的大部分为中晚期患者,胃癌的早期诊断有待进一步提高。
Objective To understand the characteristics of epidemiological and clinicopathological data of gastric cancer patients treated in our hospital in the past 6 years to provide help for the diagnosis and evaluation of the disease. Methods A total of 958 gastric cancer patients undergoing surgical treatment in our hospital from January 2004 to December 2009 were studied retrospectively on their general data, tumor pathological types, site of occurrence, clinical stage and so on. Results Among the 958 gastric cancer patients, 697 (72.8%) were male and 261 (27.2%) were female. The age ranged from 26 to 91 years, with an average of 62.6 years. The high-incidence age group was 46 to 65 years old (49.4%, 473/958), followed by ≥66 years and ≤45 years, respectively, 42.3% (405/958 ) And 8.3% (80/958). The majority of pathological types were Borrmann Ⅱ (70.1%). The majority of pathological types were adenocarcinoma (82.3%) and signet-ring cell carcinoma (7.8%). The degree of differentiation was poorly differentiated (46.9%). Occurred to the majority of cardia, accounting for 53.0%. The TNM clinical stage is mainly in stage Ⅲ, accounting for 47.4%. Conclusions ① The gastric cancer is more common in middle-aged and elderly male patients, with cardia poorly differentiated adenocarcinoma more common, gastric cardia cancer incidence was significantly higher than that of gastric cancer; ② in patients with gastric cancer, a higher degree of malignancy poorly differentiated, signet-ring cell carcinoma The highest proportion of patients were relatively younger patients (≤ 45 years old group); ③ The majority of surgical treatment of advanced patients, the early diagnosis of gastric cancer to be further improved.