贫血是大多数骨髓增生异常综合征(MDS)患者的一个问题。应用铁动力学技术可研究贫血的机理:这些方法是有用的,但耗时。有几个报告报道过MDS的铁动力学异常。Hast以及Reizenstein应用了传统的方法测定血浆铁清除率及红细胞铁掺入率。其他学者应用多种方法定量测定有效及无效性铁转换率。除了一个研究外,在FAB分类法建立以前的全部铁动力学研究都已发表。在1977年Hast以及Reizenstein所研究的病例不能按FAB分类法再进行分类,因为缺乏骨髓环状铁粒幼细胞及血中单核细胞计数的资料。但如根 Anemia is a problem in most patients with myelodysplastic syndromes (MDS). The mechanism of anemia can be studied using iron-kinetic techniques: these methods are useful but time-consuming. Several reports have reported abnormalities in iron dynamics in MDS. Hast and Reizenstein applied traditional methods to determine plasma iron clearance and red blood cell iron incorporation. Other scholars use a variety of methods to quantitatively determine the effective and ineffective iron turnover rates. With the exception of one study, all previous studies of iron dynamics have been published before the establishment of the FAB taxonomy. The cases studied by Hast and Reizenstein in 1977 can not be further classified by FAB classification due to a lack of data on bone marrow ring-shaped myeloid granulocytes and monocytes in the blood. But like roots