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前列腺素E_1(PGE_1)是一种高效活性物质,具有抑制血小板聚集、防止动脉粥样硬化(AS)形成及舒张血管平滑肌的作用。本研究应用随机双盲对照法,对脑梗塞患者,分别予PGE_1或常规药物(维脑路通、胞二磷胆碱)治疗,观察临床疗效。1 临床资料1.1 对象与分组 自1997年6月至1998年10月我科收治的发病48小时内脑梗塞患者158例,入院时行颅脑CT或MRI检查,依据1986年中华医学会第二次全国脑血管病学术会议第三次修订的脑梗塞诊断标准确诊。患者随机分为治疗组(PGE_1组)和对照组(常规药物组)。治疗组:80例,男性48例,女性32
Prostaglandin E_1 (PGE_1) is a highly active substance that inhibits platelet aggregation, prevents atherosclerosis (AS) formation and relaxes vascular smooth muscle. In this study, a randomized double-blind control method, for patients with cerebral infarction, were given PGE_1 or conventional drugs (Venoruton, citicoline) treatment, observation of clinical efficacy. 1 clinical data 1.1 objects and subgroups from June 1997 to October 1998 in our department admitted 158 cases of cerebral infarction within 48 hours of onset, admission CT or MRI brain examination, according to the 1986 Chinese Medical Association second The National Cerebrovascular Disease Conference revised the third diagnosis of cerebral infarction diagnostic criteria. Patients were randomly divided into treatment group (PGE_1 group) and control group (conventional drug group). Treatment group: 80 cases, 48 males and 32 females