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目的:观察小鼠对维通注射液的急性毒性反应。方法:小鼠随机分为5组,各组注射不同浓度维通注射液,观察小鼠的活动与毒性反应,根据小鼠死亡情况计算出LD50。结果:维通注射液的LD50为8.4mg/kg。结论:维通注射液具有良好的安全性,实验所获得的LD50值可为其药理学药效学等的研究提供依据。
Objective: To observe the acute toxicity of mice to Weitong injection. METHODS: Mice were randomly divided into 5 groups. Each group was injected with different concentrations of Weitong injection. The activity and toxicity of the mice were observed. The LD50 was calculated based on the death of mice. Results: The LD50 of Weitong injection was 8.4mg/kg. Conclusion: Weitong injection has good safety, and the LD50 value obtained from the experiment can provide a basis for pharmacological pharmacodynamic studies.