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本文根据体视学原理,对20例胃粘膜上皮异型增生和20例高分化腺癌共80个病灶中的间质细胞进行定量研究。结果显示:胃癌和异型增生组织中间质细胞体积密度分别为0.1382±0.0124,0.1761±0.0083。胃粘膜上皮异型增生病变中间质细胞明显多于高分化腺癌(P<0.05)。这种体视学参数可作为鉴别异型增生和高分化腺癌的一种新的参考指标。
Based on the principles of stereology, this study quantified the mesenchymal cells in 20 cases of gastric epithelial dysplasia and 20 cases of well-differentiated adenocarcinoma. The results showed that the volume densities of interstitial cells in gastric cancer and dysplasia were 0.1382±0.0124 and 0.1761±0.0083, respectively. The number of mesenchymal cells in gastric epithelial dysplasia was significantly higher than that in well-differentiated adenocarcinoma (P<0.05). This stereological parameter can be used as a new reference for identifying dysplasia and well-differentiated adenocarcinoma.