Experimental Study on the Antitussive,Apophlegmatic and Antiasthmatic Effect of Extract of Jianhua

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[Objective]To explore the antitussive,apophlegmatic and antiasthmatic effect of extract of Jianhua. [Methods]The antitussive, apophlegmatic and antiasthmatic effect of extract of Jianhua was studied by animal models. Control group,low-dosage group of extract of Jianhua,medium-dosage group of extract of Jianhua,high-dosage group of extract of Jianhua and positive medication group were included in the experiment. [Results] Compared with control group,low,medium and high-dosage of aqueous extract and alcohol extract of Jianhua could significantly inhibit cough induced by stronger ammonia water( P < 0. 05,P < 0. 01); medium and high-dosage of aqueous extract and alcohol extract of Jianhua could significantly increase phenol red excretion in the respiratory tract of mice( P < 0. 05,P < 0. 01); high-dosage of aqueous extract and alcohol extract of Jianhua could significantly prolong the incubation of asthma in guinea pigs induced by citric acid( P < 0. 05). [Conclusions]The extract of Jianhua had significant effect of relieving a cough,eliminating phlegm and relieving asthma. [Objective] To explore the antitussive, apophlegmatic and antiasthmatic effect of extract of Jianhua. [Methods] The antitussive, apophlegmatic and antiasthmatic effect of extract of Jianhua was studied by animal models. Control group, low-dosage group of extract of Jianhua, medium -dosage group of extract of Jianhua, high-dosage group of extract of Jianhua and positive medication group were included in the experiment. [Results] Compared with control group, low, medium and high-dosage of aqueous extract and alcohol extract of Jianhua could significantly inhibited cough induced by stronger ammonia water (P <0.05, P <0.01); medium and high-dosage of aqueous extract and alcohol extract of Jianhua could significantly increased phenol red excretion in the respiratory tract of mice (P < 0. 05, P <0.01); high-dosage of aqueous extract and alcohol extract of Jianhua could significantly prolong the incubation of asthma in guinea pigs induced by citric acid (P <0.05). [Conclusions] The extract of Jianhu a had significant effect of relieving a cough, eliminating phlegm and relieving asthma.
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