目的实现组织芯片在组织学教学中的应用。方法取正常Wistar大鼠心、肝、肾、脾等器官,采用组织芯片仪制作组织微阵列蜡块,常规切片,经苏木精—伊红染色制成组织学考试用组织芯片。结果芯片中组织微阵列排列整齐,各样本组织染色清晰,组织定位良好,可判断性强。结论与传统组织切片相比,组织学考试用组织芯片具有低消耗、可比性强、简便易行、局限性小的特点,应用前景广阔。 Objective To realize the application of tissue microarray in histology teaching. Methods The heart, liver, kidney, spleen and other organs of normal Wistar rats were obtained. Tissue microarrays were prepared by tissue microarray and routinely sliced. Tissue microarray chips were made by hematoxylin-eosin staining. Results Tissue microarrays in the chip were arranged neatly, each tissue was stained clearly, the tissue was well located and its judgment was strong. Conclusion Compared with the traditional histological sections, histological examination of the tissue microarray has the characteristics of low consumption, comparability, simple and easy operation and small limitation, and has wide application prospect.