近年来,有调查表明,大骨节病区粮食中可检出数种镰刀菌毒素,且含量较非病区高。若将镰刀菌毒素作为本病的病因,有两个问题尚需明确。①是否在所有的大骨节病区粮食中均可检出镰刀菌毒素?②大骨节病患者主食中是否有镰刀菌毒素存在?患者体内是否有该种毒素或其降解产物存在。当前,在全国大骨节病情明显下降的情况下,选择病情仍较重且有新发病例的病区作为研究现场,较不发病的轻病区或老病区对探索病因研究更有 In recent years, a survey shows that Kashin-Beck disease in the food can be detected in several species of Fusarium toxins, and the content is higher than the non-ward. If you use Fusarium toxins as the cause of this disease, there are two issues that need to be clarified. ① whether Fusarium toxins can be detected in all the food in KBD? (2) whether Fusarium toxins exist in the staple food of KBD patients, and whether the toxins or their degradation products exist in the patients. Currently, in the case of a significant decline in the bones of the country, the selection is still serious and there are new cases of the ward as a research site, less disease of the light or old ward to explore the cause of the disease more