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[目的]应用Meta分析探讨被动吸烟与乳腺癌的相关性。[方法]全面检索CHKD、CBM、VIP和Medline等中英文数据库,收集2001～2011年发表的被动吸烟与乳腺癌发病风险的相关文献。应用统计学软件对文献数据进行统计分析。[结果]共11项研究被纳入分析。11项研究存在异质性(Q=32.68,P=0.000),采用随机效应模型进行合并计算,合并RR值为1.23,合并95%CI为1.12～1.40。[结论]被动吸烟是乳腺癌的易感因素,通过各种方法减少被动吸烟,可以有效降低乳腺癌的发病风险。
[Objective] To investigate the relativity between passive smoking and breast cancer by Meta-analysis. [Methods] A comprehensive search of Chinese and English databases such as CHKD, CBM, VIP and Medline was conducted to collect the relevant literature on the risk of passive smoking and breast cancer published from 2001 to 2011. Statistical analysis of literature data is made using statistical software. [Results] A total of 11 studies were included in the analysis. Eleven studies showed heterogeneity (Q = 32.68, P = 0.000). The random effects model was used for the combined calculation. The combined RR was 1.23 and the 95% CI was 1.12-1.40. [Conclusion] Passive smoking is a predisposing factor of breast cancer. Passing various ways to reduce passive smoking can effectively reduce the risk of breast cancer.