迄今为止的国内外研究均巳表明,在现阶段,环境铅污染已经成为影响儿童生长发育的重要因素,而且铅毒性一旦发生,即难逆转,因此,预防比治疗具有更重要更积极的意义。从环境医学的角度出发,最根本的预防措施是消除环境铅污染或脱离铅污染环境,但这在目前尚不能做到,而在现有条件下,对铅污染地区高危儿童采取预防性给药,尽可能减少铅的吸收,是较为现实可行的措施。我们在建立动物模型的的基础上发现,在铅暴露同时补以等量钙能明显减低铅暴露幼鼠的血铅水平,其学习记忆能力亦几乎不受损害。在此基础上,我们进行了服用钙剂后自身前后血铅水平比较的临床验证,结果提示,铅圬染区儿童服用钙剂1个月后,86％的儿童血铅值有不同程度的下降,平均降幅达0.50μuml/L,血铅过高的儿童从服药前的50％下降到3％,这一结果证实了钙能有效抑制铅的吸收过程,为此,我们认为,对处于铅污染环境而暂时无条件脱离环境的早幼儿童应常规服用钙剂,以减轻铅对生长发育的损害。 So far both domestic and foreign studies have shown that at this stage, environmental lead pollution has become an important factor affecting children’s growth and development, and once the lead toxicity, that is difficult to reverse, therefore, prevention is more important and more positive than treatment. From the perspective of environmental medicine, the most fundamental precautionary measures are to eliminate environmental lead pollution or lead pollution from the environment, but this can not be done at present, and under the existing conditions, prophylactic administration to high-risk children in lead-contaminated areas , As much as possible to reduce the absorption of lead, is more realistic and feasible measure. Based on the establishment of animal model, we found that supplementing the same amount of calcium with lead exposure significantly reduced the level of blood lead in young rats exposed to lead, and their learning and memory abilities were also almost unimpaired. On this basis, we conducted a clinical validation of blood lead levels before and after taking calcium itself, and the results showed that after 1 month of taking calcium in children with lead-contaminated area, the blood lead levels of 86% of children had different degrees of decline , An average decline of 0.50μuml / L, high blood lead in children from 50% before taking medicine dropped to 3%, the results confirmed that calcium can effectively inhibit the absorption of lead, for which we believe that in the lead pollution Environment and temporary unconditional out of the environment of young children should take regular calcium, to reduce lead damage to growth and development.