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目的了解戊型肝炎有无慢性化趋势及其程度。方法对我国新疆南部某乡1986年1月暴发流行的戊型肝炎病人106例进行临床回顾、现症、实验室、B超等方面的调查。结果106例戊肝病人中有48例(45.28%)不同程度反复出现消化症状有36例(33.96%)有明显的右侧肋下压痛、蜘蛛痣、及及腹壁静脉曲张体征;血清免疫标记物检测:HEVIgM阳性1例(0.94%)、HEVIgG阳性55例(51.89%)、HBsAg阳性5例(4.72);血清丙氨转氨轻度生高14例(13.21%)、A/G比例改变41例(38.68%);B超声像图肝胆改变36例(48脏/次)(33.96%)。符合慢性肝炎诊断的41例(38.68%)。结论戊型肝炎病后51.89%抗HEVIgG可持续阳性,至少18年以上。在流行病学上有较大的意义。有38.68%(41/106)成为慢性肝炎,大部分为慢性迁延型。未见肝硬化。
Objective To understand the trend of chronic hepatitis E and its extent. Methods One hundred and sixty cases of hepatitis E patients outbreak in a village of southern Xinjiang in January 1986 were investigated retrospectively. Results Of the 106 patients with hepatitis E, 48 (45.28%) had signs of right subcostal tenderness, spider nevus, and varicose veins in 36 cases (33.96%) with varying degrees of recurrent digestive symptoms. Serum immune markers The positive rate of ALT in serum was 14 (13.21%) and the ratio of A / G was changed 41 (55%), Cases (38.68%); B ultrasound image of hepatobiliary changes in 36 cases (48 dirty / times) (33.96%). In line with the diagnosis of chronic hepatitis in 41 cases (38.68%). Conclusion 51.89% of anti HEVGG positive after hepatitis E disease were positive for at least 18 years. In epidemiology has great significance. 38.68% (41/106) became chronic hepatitis, most of them chronic persistent type. No liver cirrhosis.