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目的分析广州市鼻咽癌患者的生存状况,为预后评价和防治提供依据。方法对2009年广州市肿瘤登记处的1 291例鼻咽癌的生存情况随访截止日期为2014-12-31,数据应用SPSS19.0进行统计分析,寿命表法计算观察生存,Log-rank检验比较组间肿瘤生存率,Cox回归模型进行多因素分析。结果广州市鼻咽癌患者1年、3年、5年生存率分别为85.80%、68.80%、57.89%,单因素分析显示不同性别、不同年龄、不同临床分期、不同治疗方法对鼻咽癌预后有影响,Cox多因素分析显示性别(OR=0.804)、分期(OR=1.458)、年龄分组(OR=1.338)、治疗方式(OR=1.466)是独立预后危险因素。结论广州市鼻咽癌患者生存率略高于全国平均水平,但低于中国香港,鼻咽癌防治应提高早诊率和采取有效的治疗方法。
Objective To analyze the survival status of patients with nasopharyngeal carcinoma in Guangzhou and provide evidence for prognosis evaluation and prevention. Methods The survival of 1 291 cases of nasopharyngeal carcinoma in Guangzhou Cancer Registry in 2009 was followed up by December 31, 2014. The data were analyzed by SPSS 19.0, and the survival was calculated by life table method. Log-rank test Tumor survival rate between groups, Cox regression model for multivariate analysis. Results The 1-, 3-, 5- year survival rates of NPC in Guangzhou were 85.80%, 68.80%, 57.89% respectively. Univariate analysis showed that the prognosis (OR = 1.458), age group (OR = 1.338) and treatment (OR = 1.466) were risk factors of independent prognosis. Conclusions The survival rate of patients with nasopharyngeal carcinoma in Guangzhou is slightly higher than the national average, but lower than that of Hong Kong, China. The rate of early diagnosis and treatment of nasopharyngeal carcinoma should be increased and effective treatment should be taken.