随着抗生素的广泛使用,细菌在抗生素的选择压力下耐药株不断产生,其中细菌通过基因的水平转移,获得外源性耐药基因是加快临床耐药菌株产生的重要原因。与细菌耐药基因水平转移密切相关的遗传结构有质粒、转座子、整合型 With the widespread use of antibiotics, bacterial strains are constantly emerging under the pressure of antibiotic selection. Among them, the transfer of bacteria through gene transfer to obtain exogenous drug resistance genes is an important reason for accelerating the generation of clinical drug-resistant strains. Genetic and bacterial resistance genes are closely related to the level of genetic structure of the plasmid, transposon, integrated