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目的 研究不同程度妊高征患者红细胞免疫功能的变化。方法 对 40例妊高征患者和 30例正常孕妇的红细胞C3b受体花环试验、免疫复合物 (IC)花环试验及红细胞免疫粘附 (RCIA)调节因子 (促进因子和抑制因子 )活性进行测定。结果 妊高征患者的红细胞C3b受体花环及IC花环均低于正常孕妇 (P <0 .0 1 ) ,红细胞免疫粘附抑制因子活性明显高于正常孕妇 (P <0 .0 0 1 )。结论 妊高征患者红细胞免疫功能低下 ,可作为反映妊高征病变程度的指标。
Objective To study the changes of erythrocyte immune function in patients with different stages of pregnancy-induced hypertension. Methods The erythrocyte C3b receptor rosette test, immune complex (IC) rosette test and erythrocyte immune adhesion (RCIA) regulatory factor (promoting factor and inhibitory factor) activity were determined in 40 PIH patients and 30 normal pregnant women. Results The levels of erythrocyte C3b receptor rosette and IC rosette of PIH patients were lower than those of normal pregnant women (P <0.01). The activity of erythrocyte immune adhesion inhibitor was significantly higher than that of normal pregnant women (P <0.01). Conclusion The patients with PIH have low erythrocyte immune function and can be used as an index to reflect the degree of PIH.