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目的:儿童变应性鼻炎和哮喘被认为具有相似的发病机制,但目前关于儿童变应性鼻炎伴哮喘患病率的大样本研究较少,因此该文借助循证医学的方法通过Meta分析了解儿童变应性鼻炎伴哮喘的患病率。方法:系统检索Pubmed、Science、Springer、Elsevier、Embase、BMJ Journals、万方数据库、维普数据库、中国生物医学文献数据库、中国期刊全文数据库等数据库查找关于儿童变应性鼻炎伴哮喘患病率的文献,同时追索纳入文献的参考文献。采用R3.2.3软件对各研究结果进行分析。结果:共纳入15篇Cross-sec-tional studies。Meta分析结果显示,中国变应性鼻炎患儿中伴哮喘的患病率高达35.01%(95%CI 32.32%~37.70%),国外变应性鼻炎患儿中伴哮喘的患病率达31.59%(95%CI28.02%~35.16%)。结论:变应性鼻炎患儿伴哮喘的患病率高,中国变应性鼻炎患儿伴哮喘的患病率高于国外。
PURPOSE: Children with allergic rhinitis and asthma are thought to have similar mechanisms of pathogenesis, but at present there are few large sample studies on the prevalence of allergic rhinitis in children with asthma, so this article uses Meta-analysis to understand by evidence-based medicine Prevalence of allergic rhinitis in children with asthma. Methods: The databases of Pubmed, Science, Springer, Elsevier, Embase, BMJ Journals, Wanfang Database, VIP Database, China Biomedical Literature Database, and Chinese Journal Full-text Database were searched systematically to find out the literature about the prevalence of allergic rhinitis in children with asthma , While recourse to the literature reference. The results of each study were analyzed using R3.2.3 software. Results: A total of 15 Cross-sec-tional studies were included. Meta-analysis showed that the prevalence of asthma in children with allergic rhinitis in China was as high as 35.01% (95% CI 32.32% -37.70%). The prevalence of asthma in foreign children with allergic rhinitis was 31.59% (95% CI 28.02% ~ 35.16%). Conclusion: The prevalence of asthma in children with allergic rhinitis is high. The prevalence of asthma in children with allergic rhinitis is higher than that in other countries.