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预混门冬胰岛素50含有50%的速效门冬胰岛素和50%的中效鱼精蛋白结合门冬胰岛素,在药代动力学上比预混人胰岛素50R起效更快,达峰浓度更高。因此,其除了有效降低血糖外,还能改善餐后血糖,具有低血糖风险较小,且重度和夜间低血糖发生率低的特点。预混门冬胰岛素紧邻餐时注射,使用灵活方便,当用于简单强化治疗时,与基础-餐时治疗方案有效性和安全性相当。预混门冬胰岛素50为糖尿病患者,尤其是餐后血糖偏高的患者提供了新选择。
Pre-blended Aspart Insulin 50 contains 50% aspart aspart and 50% Pro-protamine in combination with insulin aspart, which has a faster pharmacokinetic effect than pre-mixed insulin 50R with higher peak concentrations . Therefore, in addition to effectively lowering blood glucose, it can also improve postprandial blood glucose, has a low risk of hypoglycemia, and is characterized by severe and low incidence of hypoglycemia at night. The ready-to-use insulin aspart is injected immediately adjacent to the meal, providing a flexible and easy-to-use treatment that is comparable in effectiveness and safety to a basic-meal treatment when used in simple intensive treatment. Prefixed Aspart 50 is a new option for patients with diabetes, especially those with high postprandial glucose levels.