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目的探讨阴茎神经内分泌癌(NEC)的诊断、治疗和预后。方法回顾性分析2011年我院收治的1例经病理确诊的阴茎NEC患者临床资料,并复习有关文献。结果患者行阴茎部分切除术,组织学特点和免疫组化标记物提示为原发性高分化阴茎NEC(类癌)。术后未行辅助治疗,随访24个月,无肿瘤复发。结论阴茎NEC临床罕见,组织学特点和免疫组化标记物是诊断该病的主要依据。早期手术疗效良好,术后应密切随访,预防复发和转移。
Objective To investigate the diagnosis, treatment and prognosis of penile neuroendocrine carcinoma (NEC). Methods The clinical data of 1 patient with penile NEC diagnosed by pathology in 2011 in our hospital were retrospectively analyzed and the related literatures were reviewed. Results The patient underwent partial resection of the penis, histological features and immunohistochemical markers suggest that the primary well-differentiated penile NEC (carcinoid). No adjuvant postoperative treatment, follow-up 24 months, no tumor recurrence. Conclusion Penile NEC is clinically rare, histological features and immunohistochemical markers are the main basis for the diagnosis of the disease. Early surgery with good effect, should be followed up closely to prevent recurrence and metastasis.