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部分急性呼吸衰竭的病人出现左室功能不全。多巴胺可用于增加病人的心输出量和动脉血压。对于肺血管通透性改变所致的肺水肿,即便肺毛细血管楔压(Pulmonary capillary wedge pressure,PCWP)的微小变化也会影响肺水量,所以确定多巴胺对急性呼吸衰竭病人心血管系统的影响是很重要的。作者对11例因急性呼吸衰竭接受机械通气治疗的病人静脉输入多巴胺。本组病人均有弥漫的肺浸润,须吸入氧气浓度>50%方能维持足够的氧合。病人的PCWP正常或轻度升高,肺内右向左的分流率增加,无急性心肌损害和心脏瓣膜病的证据,亦无慢性阻塞
Some patients with acute respiratory failure have left ventricular dysfunction. Dopamine can be used to increase the patient’s cardiac output and arterial blood pressure. For pulmonary edema caused by changes in pulmonary vascular permeability, even small changes in pulmonary capillary wedge pressure (PCWP) can affect lung water volume, so determining the effect of dopamine on the cardiovascular system in patients with acute respiratory failure is very important. The authors received intravenous dopamine in 11 patients who received mechanical ventilation for acute respiratory failure. Patients in this group have diffuse pulmonary infiltration, to be inhaled oxygen concentration> 50% in order to maintain adequate oxygenation. Patients with normal or mild PCWP increased right lung to shunt right heart rate increased, no evidence of acute myocardial damage and valvular heart disease, nor chronic obstruction