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目的探讨短暂性脑缺血发作患者脑氧供需及凝血指标的变化规律。方法选取2010年5月-2012年2月于本院进行治疗的37例短暂性脑缺血发作患者为观察组,同时期进行体检的37名健康人员为对照组,将两组人员的脑氧代谢指标及凝血指标进行检测及比较。结果观察组颈内静脉氧含量(CjvO2)、颈内静脉血氧饱和度(SjvO2)均低于对照组,动脉血氧含量(CaO2)、颈内动静脉氧含量差(Da-jvO2)及凝血指标均大于对照组,且发作频率较高者波动幅度也更高,差异有统计学意义(P均<0.05)。结论短暂性脑缺血发作患者脑氧供需及凝血指标存在明显的异常,可为疾病的诊治提供一定的依据。
Objective To investigate the changes of cerebral oxygen supply and demand and coagulation index in patients with transient ischemic attack. Methods Thirty-seven patients with transient ischemic attack who were treated in our hospital from May 2010 to February 2012 were selected as the observation group, and 37 healthy people who took physical examination during the same period were selected as the control group. The cerebral oxygen Metabolic indicators and coagulation indicators were detected and compared. Results The CjvO2 and SjvO2 of the observation group were lower than those of the control group. The contents of CaO2, Da-jvO2 and blood coagulation The index was higher than the control group, and the higher the frequency of seizures was also higher, the difference was statistically significant (P all <0.05). Conclusion There are obvious abnormalities in cerebral oxygen supply and demand and coagulation indexes in patients with transient ischemic attack, which may provide some evidences for the diagnosis and treatment of the disease.