目的研究比较经直肠超声(transrectal ultrasound,TRUS)、超声造影(contrast-enhanced ultrasonography,CEUS)与磁共振动态增强成像(dynamic contrast material-enhanced magnetic resonance imaging,DCE-MRI)在前列腺癌诊断中的临床价值。方法回顾性分析临床疑诊前列腺癌并进一步行系统穿刺活检术的63例患者术前TRUS、CEUS、DCE-MRI的相关检查数据,结合病理组织学结果,对上述三种检查方法在前列腺癌诊断中的临床价值进行比较。结果 TRUS、CEUS、DCE-MRI对前列腺癌诊断的特异性分别为48.84%、74.42%和69.77%,敏感度分别为60%、65%和85%,诊断准确率分别为52.38%、71.43%、74.60%,TRUS、CEUS、DCE-MRI三种影像学检查方法对前列腺癌的诊断价值差异无统计学意义(P>0.05);TRUS、CEUS、DCE-MRI的ROC曲线下面积比较结果分别为0.550、0.723、0.781,其中DCE-MRI的敏感度和准确率最高。结论对疑诊前列腺癌患者的筛查中,CEUS、DCE-MRI较TRUS具有更高的准确率,而其中DCE-MRI的敏感度和准确率最高。 Objective To study the clinical value of transrectal ultrasound (TRUS), contrast-enhanced ultrasonography (CEUS) and dynamic contrast material-enhanced magnetic resonance imaging (DCE-MRI) in the diagnosis of prostate cancer value. Methods The clinical data of TRUS, CEUS and DCE-MRI in 63 patients with clinical suspicion of prostate cancer and further systematic biopsy were retrospectively analyzed. Combined with the histopathological results, the diagnostic value of the above three methods in the diagnosis of prostate cancer In the clinical value of comparison. Results The diagnostic accuracy of TRUS, CEUS and DCE-MRI in diagnosis of prostate cancer were 48.84%, 74.42% and 69.77% respectively, and the sensitivity was 60%, 65% and 85% respectively. The diagnostic accuracy was 52.38% and 71.43% There was no significant difference in the diagnostic value of TRUS, CEUS and DCE-MRI for the diagnosis of prostate cancer (P> 0.05). The areas under ROC curve of TRUS, CEUS and DCE-MRI were 0.550 , 0.723,0.781, of which DCE-MRI the highest sensitivity and accuracy. Conclusion CEUS and DCE-MRI have higher accuracy than TRUS in screening suspected prostate cancer patients, and the sensitivity and accuracy of DCE-MRI are the highest among the screening patients with suspected prostate cancer.