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对医院238例儿童肾病综合征病儿进行了医院感染的调查,其中104例发生了感染,感染率为43.7%。分析医院感染的有关因素,提出肾病综合征医院感染的高低与其类型,小儿年龄、血浆蛋白含量无关,而与住院天数、应用免疫抑制剂时间及体液免疫状态有关。提出肾病综合征时不宜用青霉素来常规进行预防感染,而应严格施行保护性隔离措施,取消综合性普通病房,建立洁净病房。医院感染的治疗应严格选用适当抗生素及免疫调节剂
A total of 238 hospitalized children with nephrotic syndrome were investigated for nosocomial infection, of which 104 were infected with an infection rate of 43.7%. Analysis of related factors of nosocomial infection suggested that nosocomial infection in nephrotic syndrome was not related to its type, age of children and plasma protein content, but was related to hospitalization days, immunosuppressant time and humoral immunity status. Proposed nephrotic syndrome should not be used routinely penicillin to prevent infection, but should be strictly implemented protective isolation measures, abolition of general ward, the establishment of clean ward. The treatment of nosocomial infections should be strictly selected appropriate antibiotics and immunomodulators