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目的同时检测原发性痛风患者尿液转铁蛋白(TRF)、微白蛋白(mA1b)、α1-微球蛋白(α1-MG),评价该三项指标在原发性痛风早期肾损害中的诊断价值。方法采用散射比浊法对42例原发性痛风患者和30例健康体检者尿液三项指标进行联合检测分析。结果原发性痛风三项指标均有不同程度的增高,经比较差异有统计学意义。结论联合检测原发性痛风患者尿液三项指标,可以早期对其常见并发症之一的原发性痛风早期肾损害作出诊断,为临床提供早期的诊断依据,阻止或延缓原发性痛风发展至肾损伤。
Objective To evaluate urinary transferrin (TRF), microalbumin (mAb) and α1-microglobulin (α1-MG) in patients with primary gout at the same time. Diagnostic value. Methods Nephelometry was performed on 42 patients with primary gout and 30 healthy controls by nephelometry. Results The three indicators of primary gout were increased to varying degrees, the difference was statistically significant. Conclusions Combined detection of urine triad in patients with primary gout can make early diagnosis of primary renal damage caused by primary gout in one of the common complications and provide an early diagnosis basis for clinical treatment to prevent or delay the development of primary gout To kidney damage.