论文部分内容阅读
目的:探讨用痰热清注射液联合蒲地蓝口服液治疗手足口病的临床效果。方法:对2012年2月~2013年12月期间我院收治的108例手足口病患儿的临床资料进行回顾性研究。我们将这108例患儿随机分为观察组和对照组,每组各有54例患儿。我们给对照组患儿使用利巴韦林注射液和三磷酸腺苷进行抗病毒和营养心肌治疗,给观察组患儿在使用上述药物(用法与对照组患儿相同)进行治疗的基础上,联合使用痰热清注射液和蒲地蓝口服液进行治疗。治疗结束后,比较两组患儿治疗的效果。结果:观察组患儿治疗的总有效率为98.1%,对照组患儿治疗的总有效率为87%。观察组患儿治疗的总有效率明显高于对照组患儿,二者相比差异具有显著性(P<0.05)。观察组患儿中有5例患儿出现了不良反应,对照组患儿中有13例患儿出现了不良反应。观察组患儿出现不良反应的人数明显少于对照组患儿,二者相比差异具有显著性(P<0.05)。观察组患儿体温恢复正常的用时、皮疹消退的用时、口腔溃疡消退的用时和病情持续的时间均明显少于对照组患儿,二者相比差异具有显著性(P<0.05)。讨论:用痰热清注射液联合蒲地蓝口服液治疗手足口病疗效确切,可有效地减少患儿临床症状持续的时间,缩短其治疗的时间。此疗法值得在临床上推广使用。
Objective: To investigate the clinical effect of Tanreqing injection combined with Pudilan oral liquid in the treatment of hand, foot and mouth disease. Methods: The clinical data of 108 cases of HFMD in our hospital from February 2012 to December 2013 were retrospectively studied. We divide the 108 children into the observation group and the control group randomly, each with 54 cases in each group. We use ribavirin injection and adenosine triphosphate (ATP) to treat myocarditis in infants who are in the control group and treat the observation group on the basis of the treatment of the above-mentioned drugs (the same as the control group) Hyperthermia injection and Pudi Lan oral solution for treatment. After treatment, the effect of treatment in two groups was compared. Results: The total effective rate of treatment group was 98.1% in the observation group and 87% in the control group. The total effective rate of observation group was significantly higher than that of control group, the difference was significant (P <0.05). Adverse reactions occurred in 5 of the children in the observation group and in 13 of the children in the control group. The number of adverse reactions in the observation group was significantly less than that in the control group, the difference was significant (P <0.05). When the body temperature of the observation group returned to normal, the rash subsided, the duration of oral ulcer subsided and the duration of the disease were significantly less than those in the control group. There was significant difference between the two groups (P <0.05). Discussion: Tanreqing injection combined with Pudican oral solution for the treatment of hand, foot and mouth disease is effective, can effectively reduce the duration of clinical symptoms in children and shorten the treatment time. This therapy is worth promoting in clinic.