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为观察硒对肺炎支原体肺炎的治疗效果,采用双盲随机对照实验:选择住院支原体肺炎患儿,分为补硒组26例,病例对照组21例,正常组21例。一次补硒量为1mg亚硒酸钠,对照病例组给予常规治疗。临床结果表明,与对照组相比,治疗后补硒组的症状和体征缓解天数均有不同程度缩短(P<0.05),补硒组白细胞硒和谷胱甘肽过氧化物酶水平显著上升(P<0.05),细胞免疫功能有所改善。本研究结果提示,感染时机体内硒的代谢加速,使硒的需要量增加,补硒可减轻病情和/或加速病变恢复
In order to observe the therapeutic effect of selenium on mycoplasma pneumoniae pneumonia, a double-blind randomized controlled trial was conducted. The children with mycoplasmal pneumonia were divided into selenium-supplemented group (26 cases), 21 cases in the control group and 21 cases in the normal group. A selenium dosage of 1mg sodium selenite, control group given conventional treatment. The clinical results showed that compared with the control group, the number of symptoms and the number of days of symptom relief in the selenium group after treatment were both shortened to varying degrees (P <0.05), and selenium levels and selenium glutathione peroxidase Increased (P <0.05), and cellular immune function improved. The results of this study suggest that selenium metabolism is accelerated at the time of infection and the need for selenium is increased. Selenium supplementation may reduce the severity of the disease and / or accelerate the recovery of the disease