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卵巢癌在妇科恶性肿瘤中致死率较高,早期难以发现,对化疗易耐药,而且易转移复发,5年存活率低于30%。TSCs学说认为卵巢癌易耐药、复发及转移,根源在于TSCs所致,只有针对TSCs进行特异性治疗,才能进一步提高对卵巢癌的治疗效果。本文就卵巢癌TSCs分离鉴定、靶向治疗的研究现状及其展望作一综述。
Ovarian cancer in gynecological malignancies higher mortality, difficult to find early, resistant to chemotherapy, and easy to metastasis and recurrence, 5-year survival rate of less than 30%. TSCs doctrine that the resistance to ovarian cancer, recurrence and metastasis, the root cause of TSCs, only for specific treatment of TSCs in order to further improve the treatment of ovarian cancer. This review summarizes the research status and prospect of the isolation and identification of ovarian cancer TSCs and targeted therapy.