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本研究的目的是通过建立硒缺乏动物模型，观察硒缺乏和运动的联合作用对心肌线粒体心磷脂含量和细胞色素Ｃ氧化酶活性的影响。结果显示：安静状态下硒缺乏大鼠的心肌线粒体心磷脂含量和细胞色素Ｃ氧化酶活性与硒充足大鼠没有显著性差别。急性运动后，①硒缺乏大鼠的心磷脂含量呈降低趋势，并显著低于同组补硒大鼠，②补硒大鼠的细胞色素Ｃ氧化酶活性增加，并显著高于安静补硒大鼠，但硒缺乏大鼠没有呈现这种变化，并低于补硒大鼠。长期训练的硒缺乏大鼠的心磷脂含量显著低于补硒训练大鼠。这些结果提示，具有良好硒营养状态的机体在运动应激中提高能量代谢酶的活性以适应机体的需要，而硒缺乏的机体对运动应激不能作出适应性改变。
The purpose of this study was to investigate the effects of selenium deficiency and exercise on myocardial mitochondrial cardiolipin levels and cytochrome C oxidase activity by establishing a selenium-deficient animal model. The results showed that selenium-deficient rats had no significant difference in myocardial mitochondrial cardiolipin content and cytochrome C oxidase activity compared with adequate selenium rats. After acute exercise, the levels of cardiolipin in selenium-deficient rats tended to decrease, and were significantly lower than those in selenium-fed rats of the same group. (2) The activities of cytochrome C oxidase in selenium-enriched rats increased significantly Rats, but selenium deficiency rats did not show this change, and lower than selenium rats. Long-term training of selenium deficiency in rats with cardiolipin levels were significantly lower than selenium training rats. These results suggest that the body with good selenium nutritional status enhances the activity of energy metabolism enzymes to meet the needs of the body during exercise stress, while the selenium-deficient body can not make adaptive changes to exercise stress.