阿莫西林与头孢哌酮钠治疗大叶性肺炎的临床疗效

来源 :中国药物经济学 | 被引量 : 0次 | 上传用户:zml19881209
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目的探讨阿莫西林与头孢哌酮钠治疗大叶性肺炎临床治疗效果。方法选择2012年9月至2013年10月在我院进行大叶性肺炎治疗的50例患者资料进行研究和分析,将其分为两组,对全部患者行对症治疗,在此治疗基础上对照组患者给予阿莫西林治疗,治疗组患者给予头孢哌酮钠治疗,对两组患者的临床治疗效果进行比较和分析。结果两组患者肺部啰音消失时间差异具有统计学意义(P<0.05),其他观察指标差异不具有统计学意义(P>0.05)。对照组1例患者头晕头痛,2例患者呕吐,1例患者皮肤瘙痒,不良反应发生率为16%,治疗组1例患者头晕头痛,1例患者腹泻,1例患者皮肤瘙痒,不良反应发生率为12%,两组患者不良反应发生率差异不具有统计学意义(P>0.05)。结论对大叶性肺炎患者行阿莫西林与头孢哌酮钠治疗均能够取得显著疗效,采用头孢哌酮钠能够加快缓解和改善患者的临床症状。 Objective To investigate the clinical effect of amoxicillin and cefoperazone sodium in the treatment of lobar pneumonia. Methods Fifty patients with lobar pneumonia treated in our hospital from September 2012 to October 2013 were studied and analyzed. The data were divided into two groups and all patients were treated symptomatically. On the basis of this treatment, Patients in group A were given amoxicillin. Patients in treatment group were treated with cefoperazone sodium. The clinical effects of two groups were compared and analyzed. Results There was significant difference in the disappearance time of pulmonary rales between the two groups (P <0.05). There was no significant difference between other two groups (P> 0.05). In the control group, 1 patient had dizziness, headache, vomiting in 2 patients and pruritus in 1 patient. The incidence of adverse reactions was 16%. One patient in the treatment group had dizziness and headache, 1 patient had diarrhea, 1 patient had pruritus and the incidence of adverse reactions Was 12%. There was no significant difference in the incidence of adverse reactions between the two groups (P> 0.05). Conclusion The treatment of patients with lobar pneumonia with amoxicillin and cefoperazone sodium treatment can achieve a significant effect, the use of cefoperazone sodium can speed up the remission and improve the clinical symptoms of patients.
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