Immune Safety of a Novel Oncolytic Mutant M1 after Administration In Vivo

来源 :Journal of Huazhong University of Science and Technology(Med | 被引量 : 0次 | 上传用户：tfgzs888

【摘要】

：

The aim of this study was to evaluate the safety and efficiency of a novel,oncolytic adenovirus mutant M1 administered in conjunction with immunosuppressive age

【作者】

：

姜利军周晓曦李钦璐于飞黄亮马全富周剑峰曹阳

【机构】

：

DepartmentofHematology,DepartmentofGynecologyandObstetrics

【出处】

：

Journal of Huazhong University of Science and Technology(Med

【发表日期】

：

2012年4期

【关键词】

：

ADENOVIRUS M1 immunity SAFETY adenovirus M1 immunity safety

下载到本地 , 更方便阅读

下载此文赞助VIP

声明 : 本文档内容版权归属内容提供方 , 如果您对本文有版权争议 , 可与客服联系进行内容授权或下架

论文部分内容阅读

The aim of this study was to evaluate the safety and efficiency of a novel,oncolytic adenovirus mutant M1 administered in conjunction with immunosuppressive agents.Animal models were established by administering purified M1 either intravenously or retrope

其他文献

Noninvasive Measurement of Liver Fibrosis by Transient Elastography and Influencing Factors in Patie

The noninvasive measurement of liver stiffness (LS) was evaluated by transient elastogra-phy (FibroScan) and the possible influencing factors from the patients&

期刊

chronichepatitisBLIVERstiffnessFIBROSCANLIVERFIBROSISchronic hepatitis B

Impact of Luteinized Unruptured Follicles on Endometrial Receptivity

This study examined the impact of luteinized unruptured follicle (LUF) on endometrial receptivity. The menstrual cycle of 17 LUF patients (LUF group) and 13 ovu

期刊

子宫内膜卵泡破裂免疫组织化学法化学发光检测胚胎着床无血清对照组luteinized unruptured follicle endometri

Characteristics of Neutrophils Infiltration in Ventilation-induced Lung Injury

Neutrophils play a critical role in ventilation-induced lung injury. This study was aimed to investigate the characteristics of neutrophils influx in lungs indu

期刊

CHARACTERISTICINFILTRATIONNEUTROPHILventilation-inducedLUNGINJURYcharacter

Silencing Endothelin-3 Expression Attenuates the Malignant Behaviors of Human Melanoma Cells by Regu

Endothelin-3 (ET-3) is aberrantly expressed in both metastatic melanoma tissues and cultured melanoma cells.Our previous work showed that ET-3 could promote sur

期刊

恶性黑色素瘤SPARC细胞增殖性行为内皮素NF-KB人类水melanoma short hairpin RNA endothelin-3

基于增量矩阵分解的推荐系统研究

矩阵分解(Matrix Factorization, MF)属于推荐系统中的一种应用广泛且较为经典的算法。它是基于用户行为的推荐算法,被广泛知道的是矩阵分解算法是一种很好的推荐算法。在Net

期刊

矩阵分解推荐系统评分预测增量更新

腹腔镜左半肝切除在肝内胆管结石患者中的治疗效果分析

目的探讨左肝内胆管结石患者接受腹腔镜循肝中静脉入路解剖性左半肝切除术治疗的效果及复发率。方法选取本院2017年6月—2019年6月收治的左肝内胆管结石患者50例作为研究对象

期刊

肝中静脉左半肝切除术左肝内胆管结石腹腔镜解剖性效果复发率 middle hepatic veinleft hemihepatecto

棉纤维的功能性技术研究进展

棉纤维是一种天然纤维素类大宗纤维,其性能优异及衍生物结构复杂,在棉织物等方面有着广泛应用;也是化学工业的重要原料。作者通过查阅文献资料,针对棉纤维的溶解、物理改性、

期刊

棉纤维功能性改性技术研究进展 Cotton fiberFunctionalModification technologyResearch p

乳酸检测在新生儿窒息后脑损害中的应用价值

目的探讨出生窒息新生儿入院24 h内动脉血乳酸检测在新生儿窒息后脑损害中的应用价值。方法选取2017年8月—2019年8月福州市第一医院NICU收住的出生窒息新生儿180例为研究对

期刊

乳酸新生儿窒息缺氧酸中毒脑损害预后 lactic acidneonatal asphyxiahypoxiaacidosisbrai

CTCs与结直肠癌病理特征及术后复发的关系研究

目的通过检测结直肠癌患者术前外周血循环肿瘤细胞(CTCs),探讨结直肠癌患者术前CTCs检出水平与临床病理特征及预后的关系。方法收集2017年3月1日—2019年6月30日的40例结直肠

期刊

结直肠癌 CTCS 肿瘤部位无瘤生存期脉管癌栓预后 colorectal cancerCTCstumor locationtumor f

Epidemiological Features of Allergic Rhinitis in Four Major Cities in Western China

Allergic rhinitis(AR),with an increasing uptrend of the prevalence in many developed and developing countries,is a global health problem that affects people of

期刊

流行病学特征中国西部过敏性鼻炎城市乌鲁木齐患病率发展中国家年龄组western China epidemiology intermitten

Immune Safety of a Novel Oncolytic Mutant M1 after Administration In Vivo

与本文相关的学术论文