应用微囊技术大规模培养杂交瘤细胞以生产大量单克隆抗体,国际上已有专利。我国亟需解决此问题,为此作者对杂交瘤细胞在微囊内静态培养的生长动态特性、细胞的峰值浓度、生物学功能、形态特征以及影响囊内杂交瘤细胞满囊比的主要因素等进行了观察。结果表明:静态培养一周,细胞的峰 The use of microcapsule technology to cultivate hybridoma cells on a large scale to produce a large number of monoclonal antibodies has been patented internationally. Our country urgently needs to solve this problem. For this reason, the authors studied the growth dynamic characteristics, peak cell concentration, biological functions, morphological characteristics of hybridoma cells in static culture in microcapsules, and the main factors affecting the ratio of full cell vesicles in hybridoma cells. Observed. The results showed that: static culture for one week, the peak of the cells