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皮肌炎的血浆交换疗法(plasma exchange,PE)是Brewer1980年报告的。日本在1984年由寺井等首先报告。这些病例均为小儿皮肌炎,认为用PE法是清除了小儿体内γ-球蛋白补体免疫复合物,从而改善症状。对成人型皮肌炎病因尚不十分明确,几乎未见到这类病人的PE疗法报告。本文作者试用PE疗法治疗抗类固醇和免疫制剂的成人型皮肌炎病例获得良好效果,介绍如下。病例23岁、男、面部红斑、四肢肌力低下。根据临床症状、血中肌原性酶升高,皮肤肌肉活检所见及肌电图的表现确诊为皮肌炎而入院。开始予以培他米松6mg/日,口服,症状有所改善,1个月后改善停
Dermatomyositis plasma exchange (PE) was reported by Brewer in 1980. Japan was first reported by Terai in 1984. These cases are pediatric dermatomyositis, that the use of PE is to clear the body of children with gamma-globulin complement immune complexes, thereby improving the symptoms. The cause of adult dermatomyositis is not yet fully understood and few reports of PE therapy have been reported in these patients. The authors of the trial of PE therapy for anti-steroid and immunosuppressive adult dermatitis cases obtained good results, described below. Case 23 years old, male, facial erythema, low limb muscle strength. According to clinical symptoms, elevated myogenic enzymes in the blood, skin muscular biopsy seen and the performance of electromyography diagnosed as dermatomyositis and admission. Began to pemetrexed 6mg / day, oral, symptoms have improved, improve after 1 month stop