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1例75岁男性患者因椎-基底动脉供血不足给予丹红注射液20 ml入5%葡萄糖注射液250 ml静滴。静脉滴注开始后约1~2 min,患者出现面部发热伴瘙痒、双眼睑及口唇肿胀、咽部紧缩感、呼吸困难、心慌、出冷汗。查体:HR 136次/min,BP50/30 mm Hg。立即停用该药,给予吸氧、肾上腺素、多巴胺、地塞米松等治疗。12 h后生命体征平稳,无不适感出院。
A 75-year-old male patient received 20 ml of Danhong injection and 250 ml of 5% dextrose injection due to insufficiency of vertebro-basilar artery. About 1 to 2 minutes after the start of intravenous drip, the patient developed facial fever with itching, swelling of both eyelids and lips, sense of throat tightening, dyspnea, palpitation, and cold sweat. Physical examination: HR 136 times / min, BP50 / 30 mm Hg. Immediately discontinue the drug, given oxygen, epinephrine, dopamine, dexamethasone and other treatment. After 12 h, the vital signs were stable without any discomfort.