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[目的]研究巴曲亭-注射用蛇毒血凝酶在结肠癌手术患者手术中及手术后止血的有效及安全性。[方法]选取本院行手术治疗的住院病人160例,随机分为两组,巴曲亭实验组及生理盐水对照组手术前30min及术后d1～3观察两组病人术中伤口渗血及术后引流管引流液情况。[结果]实验组病人术中伤口渗血量较对照组少,术后引流血量也较少,与对照组比较差异有统计学意义(P﹤0.05)。实验组病人未出现用药相关并发症。[结论]巴曲亭能有效地减少结肠癌手术患者手术中出血和术后渗血或再出血,疗效明确,并未出现并发症,临床应用安全有效。
[Objective] To study the efficacy and safety of batriking-injection of snake venom hemagglutinin for hemostasis during and after operation of colon cancer surgery. [Methods] A total of 160 hospitalized patients undergoing surgery in our hospital were randomly divided into two groups. The experimental group and the normal saline control group were treated with 30 min before operation and 1 d-3 after operation. Drainage after the drainage tube fluid situation. [Results] The bleeding volume of the experimental group was less than that of the control group, and the amount of bleeding after operation was also lower. There was significant difference between the experimental group and the control group (P <0.05). The experimental group patients did not appear drug-related complications. [Conclusion] Batrituting can effectively reduce bleeding and postoperative bleeding or rebleeding after operation in patients with colon cancer. The curative effect is clear and no complications are found. It is safe and effective in clinical application.