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目的 :比较后程加速超分割放疗并用安卡治疗与常规放疗 ,常规放疗并用安卡治疗鼻咽癌的效果及毒副作用。方法 :将 96例鼻咽癌随机分为 3组 ,常规放疗组 (常放组 )、常规放疗加用安卡组 (药放组 )、后程加速超分割放疗并用安卡组 (后程组 ) ,3组病例肿瘤量相同。结果 :放疗结束时鼻咽癌原发灶全消率 ,常放组、药放组和后程组分别为 62 .5%、83.3%、82 .4 %。半年复查 ,3组全消率分别为68 8%、86.7%、91.2 % ,后程组明显高于常放组P <0 .0 5。CT检查颈部转移淋巴结消退情况与上述结果相似。毒副作用较常规组略重 ,尚可耐受。结论 :后程组较常放组比较肿瘤全消率明显提高 ,毒副作用尚可耐受 ,值得扩大病例深入研究
OBJECTIVE: To compare the effects and toxicities and side effects of late-course accelerated hyperfractionation radiotherapy with Anka therapy and conventional radiotherapy, conventional radiotherapy and Anka therapy for nasopharyngeal carcinoma. Methods: Ninety - six NPC patients were randomly divided into three groups: conventional radiotherapy group (Changsan group), conventional radiotherapy plus Anka group (Yagan group), late course accelerated hyperfraction radiotherapy and the use of Anka group ), The same amount of tumor in 3 groups. Results: At the end of radiotherapy, the rate of primary cancers of NPC completely disappeared, which were 62.5%, 83.3% and 82.4% respectively in Changan, Yantai and later courses. Six months of review, the three groups of total elimination rates were 688%, 86.7%, 91.2%, the latter group was significantly higher than the routine release group P <0. CT examination of cervical lymph node regression and the above results are similar. Toxic side effects than the conventional group slightly heavier, tolerable. Conclusions: Compared with the control group, the complete elimination rate of the patients in the later course group is significantly increased, and the side effects are still tolerable, which is worth further study