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目的:分析高血压合并血管性认知障碍患者的血压水平及变异性特点。方法:选取2015年6月至2016年5月本院老年科住院的46例高血压合并血管性认知障碍患者作为血管性认识障碍组(VCI组),同时选取相同时间段就诊的56例仅患原发性高血压的患者作为对照组,行24 h动态血压监测,分析两组一般资料、血压变异性、动态血压特点。结果:与对照组相比,VCI组24 h平均收缩压、昼间收缩压、夜间收缩压明显升高(分别P<0.01、0.02、0.03)。结论:收缩压增高是血管性认知障碍的重要危险因素。
Objective: To analyze the characteristics of blood pressure and variability in patients with hypertension complicated with vascular cognitive impairment. Methods: Forty-six hypertensive patients with vascular cognitive impairment admitted to our hospital from June 2015 to May 2016 were enrolled in this study. Fifty-six patients with vascular cognitive impairment (VCI group) were enrolled in the same period Patients with essential hypertension as control group, 24 h ambulatory blood pressure monitoring, analysis of two general information, blood pressure variability, ambulatory blood pressure characteristics. Results: Compared with the control group, the mean systolic blood pressure, diurnal systolic pressure and nocturnal systolic pressure in VCI group were significantly increased at 24 h (P <0.01, 0.02, and 0.03, respectively). Conclusion: Increased systolic blood pressure is an important risk factor for vascular cognitive impairment.