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目的：探讨晚期血吸虫病（晚血）的护理干预措施。方法收集2008-2013年入住本院的52例晚血患者病例资料，总结护理措施。结果52例晚血患者中，男性38例，女性14例；年龄57~75岁，平均65.8岁。53.8%患者间接血凝试验（IHA）阳性，67.3%酶联免疫吸附试验（ELISA）阳性；21.2%HBsAg阳性。腹水型患者13例，巨脾型34例，侏儒型5例。经过相应治疗辅以护理干预后，73.1%得到临床治愈，23.1%病情稳定，3.8%病情好转。主要护理干预措施包括一般基础护理、饮食护理、治疗护理、心理护理和手术护理。结论采取科学合理的护理干预措施可提高晚血疗效，改善预后，提高患者生活和生命质量。“,”Objective To explore the reasonable nursing interventions of advanced schistosomiasis patients. Methods The medical records of 52 advanced schistosomiasis patients hospitalized from 2008 to 2013 were collected,and the nursing interven-tions were summarized. Results The 52 cases of advanced schistosomiasis included 38 men and 14 women,with a mean age of 65.8 years(57-75 years). Totally 53.8%of the subjects were schistosome positive by IHA test,67.3%positive by ELISA,and 21.2%positive of HBsAg. There were 13 cases of ascites type,34 cases of megalosplenia type,and 5 cases of dwarfism type of ad-vanced schistosomiasis. Following the therapy together with nursing interventions,73.1%achieved clinical cure,23.1%achieved stable,and 3.8%achieved improvement. The major nursing interventions involved basic nursing,diet nursing,treatment nursing, physiological nursing and surgical nursing. Conclusion The scientific and reasonable nursing interventions can improve the ther-apeutic efficacy and prognosis in advanced schistosomiasis patients,as well as improve their quality of life.