时间生物学研究认为,机体的代谢和功能都具有明显的节律性变化,其中研究最多的是昼夜节律.许多血液学参数,如骨髓细胞的有丝分裂活性、外周血淋巴细胞和嗜伊红细胞计数、血浆铁浓度等都有生理节奏周期,所以评价实验结果时应考虑到正常动物的生理节奏周期。我们对在正常饲养条件下的大鼠睾丸有丝分裂昼夜节律进行了初步观察,结果如下: 方法 取健康雄性Wistar大鼠60只,体重180～220g, Time biology studies suggest that the body’s metabolism and function have significant rhythmic changes, of which the most studied is the circadian rhythm.Many hematological parameters, such as bone marrow cell mitotic activity, peripheral blood lymphocytes and eosinophil count, plasma Iron concentration and so have circadian rhythms, so evaluation of experimental results should be taken into account the circadian rhythm of animals. We conducted a preliminary observation of circadian rhythms of rat testis mitosis under normal conditions. The results were as follows: Sixty healthy male Wistar rats weighing 180-220 g,