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1981年至1992年收治鼻咽癌203例,男160例,女43例,平均年龄47岁。Ⅰ期7例,ⅡI期84例,Ⅲ期72例,Ⅳa期34例,Ⅵb期6例。总的5年生存率为51.4%(72/140)。各期5年生存率:Ⅰ期100%,Ⅱ期76.2%,Ⅲ期36.6%,Ⅳa期16%,Ⅳ6期0。血行转移为主要死亡原因,占死亡病例81%(42/52)。颈部淋巴结转移程度与血行转移有直接关系,N3组血行转移率高达86.9%(20/23),应联合应用化疗以降低血行转移率。治疗后鼻咽部局部复发率为21.8%(38/174),第二程放疗局部控制率为28.9%(11/38)。
From 1981 to 1992, 203 cases of nasopharyngeal carcinoma were admitted, including 160 males and 43 females, with an average age of 47 years. There were 7 cases of stage Ⅰ, 84 cases of stage ⅡI, 72 cases of stage Ⅲ, 34 cases of stage Ⅳa and 6 cases of stage Ⅵb. The overall 5-year survival rate was 51.4% (72/140). The 5-year survival rates were 100% in stage Ⅰ, 76.2% in stage Ⅱ, 36.6% in stage Ⅲ, 16% in stage Ⅳa, and stage Ⅳ6. Blood transfer as the leading cause of death, accounting for 81% of deaths (42/52). The degree of cervical lymph node metastasis is directly related to hematogenous metastasis. The rate of hematogenous metastasis in N3 group is as high as 86.9% (20/23). Chemotherapy should be used in combination to reduce hematogenous metastasis. The local nasopharyngeal recurrence rate was 21.8% (38/174) after treatment, and the second-stage radiotherapy local control rate was 28.9% (11/38).