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良性特发性震颤是一种很难解释的疾病,最常见于震颤麻痹的病人。本病是显性遗传,但遗传基因可有不同程度的表现方式。临床上约有半数的患者有阳性家族史。虽然震颤可以开始于任何年龄,但常见于中年,随年龄的进展而慢慢趋向恶化。典型患者,震颤最初见于上肢,且可局限于上肢,但以后震颤可以发生于身体的各个部分。某些患者可有声音颤抖,摇头或颏抖颤。但上述每一个症状也许就是“良性”震颤的一种变异。在严重的病例中,震颤可以造成残废。有些人甚至不能自己摄食或照顾其摄生的需求。少数者可以发生象震颤麻痹那样的强直和运动不能。作者见到某些良性特发性震颤的成年患者,他们在儿童期已有震颤,但后来震颤却消失约几十年。
Benign essential tremor is a difficult to explain the disease, the most common paralysis patients. The disease is dominant genetic, but genetic genes may have different levels of performance. About half of patients have a positive family history of clinical. Although tremor can start at any age, it is common in middle age and tends to deteriorate slowly with age. Typical patients, tremor initially seen in the upper extremities, and can be confined to the upper extremities, but later tremor can occur in various parts of the body. Some patients may have trembling sounds, shaking their heads or shaking their cheeks. However, each of these symptoms may be a variation of “benign” tremor. In severe cases, tremor can cause disability. Some people even can not even feed themselves or take care of their needs. A handful of people can develop ankylosis and motor failure like paralysis. The authors saw some adult patients with benign essential tremor who had tremor during childhood but which later disappeared for decades.