【摘 要】
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目的 探讨目标导向液体治疗对老年肺癌根治术患者术中凝血状态的影响.方法 老年肺癌根治术患者122例,随机分为两组,实施常规治疗患者61例为对照组,实施目标导向液体治疗患者6
【机 构】
：
063000,华北理工大学附属医院麻醉科063001,河北省唐山市人民医院麻醉科;
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目的 探讨目标导向液体治疗对老年肺癌根治术患者术中凝血状态的影响.方法 老年肺癌根治术患者122例,随机分为两组,实施常规治疗患者61例为对照组,实施目标导向液体治疗患者61例为观察组,比较两组患者不同时间点凝血指标、血流力学指标、乳酸的改变情况,及两组患者体液容量改变情况、治疗及预后情况.结果 两组患者T1时PT、TT、APTT、ScvO2、乳酸显著增加,FIB、SVV、CI显著降低.观察纽患者TI、T2、T3、T4时PT、TT、APTT、乳酸均明显低于对照组,FIB、SVV、ScvO2、CI均明显高于对照组,差异均有统计学意义(P＜0.05).观察组患者尿量、胶体液量均明显多于对照组,晶体液量、总输入量均明显少于对照组,并发症发生率明显低于对照组,差异均有统计学意义(P＜0.05).结论 目标导向液体治疗有助于维持老年肺癌根治术患者术中凝血指标稳定,改善血流力学指标,具有更高的安全性.
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