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白介素 5(IL 5)是调节嗜酸粒细胞在肺内募集的主要细胞因子 ,在哮喘发病机制中起关键作用。用抗IL 5单克隆抗体治疗哮喘有一定作用。从基因水平上抑制IL 5转录将成为治疗哮喘的一个新的策略。
Interleukin 5 (IL 5) is a major cytokine that regulates the recruitment of eosinophils in the lung and plays a key role in the pathogenesis of asthma. Anti-IL-5 monoclonal antibody treatment of asthma has a role. Inhibition of IL-5 transcription at the gene level will be a new strategy for the treatment of asthma.