复方米非司酮对人早孕蜕膜组织雌激素和孕激素受体mRNA水平的影响

来源 :生殖与避孕 | 被引量 : 0次 | 上传用户:stepbystep
下载到本地 , 更方便阅读
声明 : 本文档内容版权归属内容提供方 , 如果您对本文有版权争议 , 可与客服联系进行内容授权或下架
论文部分内容阅读
通过对三组 ,每组 6~ 8例 ,由人工流产得到的早孕蜕膜组织进行雌激素和孕激素受体m RNA的核酸酶保护分析表明 ,米非司酮组雌激素和孕激素受体 m RNA水平均有显著升高 (P<0 .0 5 ) ,以未服药组为对照 ,而含双炔失碳酯的复方米非司酮组相应的 m RNA变化不明显。实验结果揭示 ,在有类似的抗早孕效果情况下 ,复方米非司酮对机体雌、孕激素受体 m RNA的影响相对较小 ,可能更适宜于作为抗早孕药物 Nuclide protection of estrogen and progesterone receptor m RNA in early pregnancy decidua from three groups of 6 to 8 cases from each group showed that estrogen and progesterone receptor m RNA levels were significantly increased (P <0.05), with no medication group as a control, and an anordrin ester-containing mifepristone group m RNA did not change significantly. The experimental results revealed that in similar anti-early pregnancy effect, the compound mifepristone on the body estrogen and progesterone receptor m RNA relatively small, may be more appropriate as an anti-early pregnancy drug
其他文献