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目的探讨呼吸机联合血液透析治疗阿维菌素(AVM)中毒的效果。方法 8例阿维菌素中毒患者给予呼吸机联合血液透析治疗,分析全组的治疗情况(抽搐停止、烦躁停止和神志、自主呼吸恢复)及治疗前后的血浆肌酸激酶、肝肾功能指标。结果所有患者均治愈,抽搐、烦躁均在48 h内停止,神志、自主呼吸在96 h内恢复,且治疗后的血浆肌酸激酶、肝肾功能指标均优于治疗前,差异具有统计学意义(P<0.05)。结论呼吸机联合血液透析治疗阿维菌素中毒的效果较好,可迅速缓解症状并改善血浆指标。
Objective To investigate the effect of ventilator combined with hemodialysis on avermectin (AVM) poisoning. Methods Eight patients with avermectin poisoning were given ventilator combined with hemodialysis. The treatment of the whole group was analyzed (convulsions stopped, irritability stopped and consciousness, recovery of spontaneous breathing) and plasma creatine kinase and liver and kidney function indexes before and after treatment. Results All patients were cured, convulsions, irritability were stopped within 48 h, consciousness, spontaneous breathing recovered within 96 h, and after treatment of plasma creatine kinase, liver and kidney function indicators were better than before treatment, the difference was statistically significant (P <0.05). Conclusion The combination of ventilator and hemodialysis is effective in treating abamectin poisoning, which can relieve the symptoms and improve the plasma parameters rapidly.